Oral antivirals efficacy for the prevention of genital herpes recurrences

Genital herpes is the most frequent cause of genital ulceration in developed countries. It is a sexually transmitted disease caused by herpes simplex virus type 1 and 2 (most frequently). After a first infection immunity develops but does not fully protect against further episodes (recurrences). Symptomatic recurrent flares occur in 20% to 50% of patients. In these patients, suppressive therapy with oral antiviral agents is usually required. These agents include acyclovir, valacyclovir, and famciclovir...read more